Sneddon-Wilkinson disease treated with etanercept: report of two cases

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Sneddon-Wilkinson disease treated with etanercept: report of two cases.

Sneddon-Wilkinson disease (SWD), also known as subcorneal pustular dermatosis, is a rare, chronic eruption that is often difficult to treat, particularly in patients who do not respond to or cannot tolerate dapsone. Few case reports exist of patients with SWD treated with antitumour necrosis factor-alpha therapy. We report two patients with SWD refractory to numerous treatments, who responded t...

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[subcorneal Pustular Dermatosis. (sneddon-wilkinson Disease)].

Subcorneal pustular dermatosis is a disease that has coalescent, flaccid, recurrent pustules. We do not know everything about its etiology or pathogenesis; however, its autoimmune mechanism links it with neoplastic or immunologic diseases. First line treatment is dapsone. We describe the case of a classic subcorneal pustular dermatosis in a patient in who we could not use dapsone (sulpha drugs ...

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Sneddon- Wilkinson Disease in association with Non- Hodgkin Lymphoma

Sneddon-Wilkinson disease is a rare condition with chronic recurrent course. It may be a part of paraneoplastic manifestation of underlying malignancy. The disease is diagnosed on the basis of its characteristic clinical features and histopathology. A case of Sneddon –Wilkinson disease associated with non-hodgkin lymphoma in a 54 years old lady is presented.

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Interruption of Sneddon-Wilkinson Subcorneal Pustulation with Infliximab

Subcorneal pustular dermatosis (SCPD, Sneddon-Wilkinson disease) is a rare chronic-relapsing skin disorder that typically manifests as flaccid sterile pustules without systemic symptoms. Although the accumulation of neutrophils is acknowledged to be a hallmark of SCPD, its exact pathomechanism is still not known. Several chemotactic factors have been implicated in neutrophil recruitment and inv...

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T Sachs disease in two children: report two cases

Background and aim: Tachyx is a rare autosomal recessive and neurological disorder caused by glycosfenolipid accumulation (GM2 ganglioside) in cell lysosomes. The accumulation of GM2 ganglioside is due to the mutation in the beta-hexose aminase gene (HEXA), which reduces the activity and deficiency of the HEXA enzyme. The aim of this study was to report 2 cases of T.Sax disease.   Case report:...

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ژورنال

عنوان ژورنال: Clinical and Experimental Dermatology

سال: 2009

ISSN: 0307-6938,1365-2230

DOI: 10.1111/j.1365-2230.2008.02905.x